1styr-B2 BIOCHEMISTRY

 BIOCHEMISTRY BLOCK 2 IMPORTANT QUESTIONS

VITAMINS

1.    Classify vitamins & write 3 differences of each class

2.    Diagrammatically explain mechanism of activation of vit D

3.    Describe absorption & transport of vit B12 & name the co-enzyme form of B12

4.   Enumerate functions of vit C along with examples

5.   Write a note on folate Trap (v.v.imp)

6.Note on Biochemical role of Vit K (v.imp) 

7.Discuss and draw visual cycle (v.v.imp)

8.A labourers child was brought to clinic with bleeding, swollen gums, complaining of lethargy& delayed wound healing. History revealed that his diet was deficient in fruits, vegetables, he had only tea and bread

i.                     What is deficient vitamin

ii.                   Functions of this vitamin

9.  What type of anaemia is caused by deficiency of vit b12

10.A 69 years old man had to come with complaints of bleeding gums for several weeks. He was on bread for last couple of months on examination, his gums were swollen. There were blue and black marks on his legs. An unhealed sore was present on his right wrist. (hypochromic microcytic anaemia)

i.                     Name of deficient vitamin.

ii.                   Function of this vitamin

11. Explain 3 mechanisms in elevation of serum calcium by Vit D

12.How are liver and kidney involved in vitD deficient

13.Functions  of vit B12 and folic acid deficiency

 14. A newborn delivered in village presented in hospital emergency with haemorrhage . an injection of vit K was given

i.                     What is cause of haemorrhage

ii.                   Sources of vit K

iii.                 Biochemical role of vit K

15.  15. A 50 years old male patient complains of loss of appetite. He reveals history of alcohol abuse for last ten years. Physical examination is not significant. His Blood count reveals a normal WBC but does show an anaemia with large RBC. His serum analyses, lipase and LFT were normal. There is no evidence of pancreatic disease, liver and gastric dysfunction.

i.                     Which vit deficiency caused anaemia

ii.                   Molecular basis of large erythrocytes

iii.                 Imp dietary sources for this Vit

iv.                 Bioactive form of this Vit

16.A 79 years old man living alone was brought to clinic with history of poor nutrition, physical examination confirmed malnutrition, stool examination revealed occult blood. He had prolonged prothrombin time and bleeding time, LFT was normal. He was given injection of fat soluble vitamin that corrected bleeding time and prothrombin time

i.                     Write down functions of this vitamin & causes of deficiency

ii.                   Enumerate vitamins with antioxidant activity

iii.                 4 diagnostic measures to detect thrombin deficiency

 

 

LIPIDS

1.    1. Certain lipoproteins are enlisted as cardio protective while others are enlisted as cardio destructive elaborate role of such lipoproteins.

2.   2.  Discuss structure function and clinical significance of cholesterol.

3.  3.  Classification of lipids.

4.     4. Define and name essential fatty acids with biological importance.

5.     5. Define and name significant omega 3 fatty acid with biological importance.

6.     6. Classify complex lipids. Describe structure, function and significance of any four glycerophospholipid and four sphingolipid.

7.      7.Define and name significant eicosanoids.

 

Thanking our contributor: Muhammed Ahmed ( CR 2^nd Year)

Edited by: Aiza Anwar (publishing director)